Wednesday, 29th November
The Australasian Society for Immunology 2017 Annual Scientific Meeting
Days
Tuesday, 28th November
Wednesday, 29th November
Thursday, 30th November
Friday, 1st December
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Speakers
Plenary II: Infection and Inflammation
8:30AM - 10:30AM
Wednesday, 29th November
Plaza Auditorium
Chairs: Denise Doolan & David Tscharke
Learning from helminths: macrophages in type 2 immunity
-
Judith Allen
Anti-viral immunity: NK cells, T cells and more
-
Mariapia Degli-Esposti
Evolution of a novel mucosal protectant
-
Paul Hertzog
T follicular helper cells (Tfh) and GC B cell responses in the context of vaccines and infections
-
Shane Crotty
Morning Tea
10:30AM - 11:00AM
Wednesday, 29th November
Plaza Auditorium Foyer
Symposium III: Mucosal Immunology
11:00AM - 12:40PM
Wednesday, 29th November
Plaza Auditorium
Chairs: Sammy Bedoui & Lynette Beattie
AhR regulation of CD1d function in the intestinal epithelium.
-
Richard Blumberg
Hookworms and their secreted proteins as a novel anti-inflammatory modality
-
Alex Loukas
Type 2 immunity is a hallmark of neonatal cardiopulmonary disease
-
Claudia Nold
Characterisation and Development of unconventional T cells
-
Daniel Pellicci
Symposium IV: Cytokines, Chemokines and Immune Signalling
11:00AM - 12:40PM
Wednesday, 29th November
P6, P7 & P8
Chairs: Iain Comerford & Anne Bruestle
CCR2 and T lymphocyte biology: An old dog teaching us new tricks.
-
Shaun McColl
Bone and marrow resident macrophages regulate both hematopoietic and skeletal health and regeneration
-
Allison Pettit
Regulation of inflammasome signalling in infection
-
Si Ming Man
Interplay between the epigenome & nuclear Signaling Kinases: Novel liquid biopsy biomarkers for metastatic cancers.
-
Robert McCuaig
Lunch
12:40PM - 2:10PM
Wednesday, 29th November
Plaza Auditorium Foyer
ASI AGM
1:00PM - 2:00PM
Wednesday, 29th November
Plaza Auditorium
Workshop 5: Lymphocyte biology 2
2:10PM - 4:00PM
Wednesday, 29th November
Plaza Auditorium
Chairs: Kim Good-Jacobson & Lauren Holz
Molecular control of FOXP3
+
regulatory T cell survival and death during inflammation
-
Simon Preston
MARCH8 controls thymic epithelial cell MHC II and CD4+ T cell development
-
Haiyin Liu
Protein tyrosine phosphatase non-receptor type 2 regulates development and function of skin-resident memory CD8 T cells
-
Katharina Hochheiser
Identification of a committed precursor to the tissue-resident memory T cell fate
-
Julia E Prier
Murine ARPC1B deficiency as a novel model for human hyper IgE syndrome
-
Brigette Boast
Regulation of activated B cell differentiation by atypical chemokine receptor 4
-
Iain Comerford
Hyperactivation of PI3 kinase causes defects in human B-cell development and differentiation
-
Stuart Tangye
Workshop 6: Inflammatory Diseases and Mechanisms
2:10PM - 4:00PM
Wednesday, 29th November
P9
Chairs: Claudine Bonder & Ming Yang
Characterising the maturation of T cell polarisation in preterm and term infants and in neonatal chronic lung disease
-
Marcel F Nold
Development of an Interleukin-22 based therapy in type 2 diabetes
-
Sahar Keshvari
Phenotypic and transcriptomic findings in baseline immune cell subsets associated with IgE-mediated allergy using a childhood twin cohort
-
James Read
Acute colitis chronically alters epithelial barrier and immune tolerance responses to subsequent colitis re-activation independently of shifts in microbiota composition
-
Patrick A Hughes
Hematopoietic stem cells and their progenitors critically require autophagy to promote early engraftment following allogeneic stem cell transplantation
-
Katie E Lineburg
IL-6
classical
-signalling drives GVHD by promoting pathogenic Th17 and Th22 differentiation
-
Andrew N Wilkinson
Effector CD4
+
T cells promote glomerular inflammation via recognition of intravascular antigen presented by patrolling monocytes
-
Michael J Hickey
Workshop 7: Infection and Immunity 2
2:10PM - 4:00PM
Wednesday, 29th November
P7 & P8
Chairs: Maria Liaskos & Malcolm Starkey
High-dimensional cytometry for interrogating immunity and disease
-
Thomas M Ashhurst
A potential role for superantigen producing bacteria in tonsillar hyperplasia
-
Fiona J Radcliff
Resolving cerebral malaria by inhibiting accumulation of pathogenic monocytes in the brain microvasculature
-
Paula Niewold
Mapping protective influenza-specific CD8
+
T cell targets for HLA-A*24:02 in Indigenous populations
-
Bridie Clemens
Alterations in CD8
+
T cell phenotype and function in the peripheral blood of
PIK3CD
gain-of-function patients
-
Emily SJ Edwards
Local CD4
+
T cell immunity in the liver protects from
Salmonella
infections
-
Newton Peres
Immunological processes underlying the slow acquisition of immunity to blood-stage malaria
-
Diana S Hansen
Workshop 8: Vaccines and Immunotherapies
2:10PM - 4:00PM
Wednesday, 29th November
P6
Chairs: Sarah Hook & Christian Bryant
First evaluation in humans of a chemically attenuated
p. Falciparum
whole parasite blood-stage vaccine
-
Danielle I Stanisic
Melt electrospun 3 D lattices for the clinical scale expansion of immunomodulaotry cells including Treg and a novel CAR-T cell targeting P
2
X7
-
Simon Barry
A dual Chikungunya and Zika vaccine derived from a new replication-incompetent poxvirus vaccine system provides mice and their offspring with complete protection from infectious challenge
-
John D Hayball
Protection against relapses of disease in a mouse model of multiple sclerosis by a parasite-derived 68-mer peptide
-
Aakanksha Dixit
Protection against tuberculosis induced by pulmonary delivered recombinant Influenza A vaccine is associated with the development of lung resident CD4
+
memory T cells
-
Manuela Flórido
Mechanisms behind elotuzumab and lenalidomide dual therapy in multiple myeloma
-
Kelden Richardson
Liver-resident memory T cells can be harnessed for unprecedented protection against malaria
-
Daniel Fernandez-Ruiz
Poster Session Two
4:00PM - 5:30PM
Wednesday, 29th November
Plaza Auditorium Foyer
Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) is a TLR4-dependent mechanism with contrasted requirements for G-CSF receptors
-
Kavita Bisht
Human CD141+ DC and CD1c+ DC undergo concordant early genetic programming after activation in humanized mice
in vivo
-
Oscar Haigh
Platelets modulate the leukocyte responses to Toll-like receptor stimulation
-
Kathryn E Hally
Hsp90 inhibitors induce caspase-1-independent IL-1β processing and secretion
-
James Harris
Nanoscale bead-based tetramer enrichment and
in vitro
stimulation results in rapid antigen-specific CD8+ T cell expansion
-
Carl Haupt
Innate immune response in traumatic Spinal Cord Injury (SCI), a beneficial regulatory role for MIS416
-
Masoud Hassanpour Golakani
Examining the development of CD4
+
T helper, regulatory and memory fates using single-cell genomics
-
Ashraful Haque
Development of an
in vivo
model to study the effects of monoclonal antibody treatment of squamous cell carcinoma
-
Xuzhi (Jessica) He
The histone acetylase, HBO1, is necessary for AIRE-regulated transcription in the thymus
-
Melanie Heinlein
A phase I / II study of pegylated-Interferon-2alpha for relapsed haematological malignancy after allogeneic haematopoietic progenitor cell transplantation (HPCT)
-
Andrea Henden
Novel CD8
+
T-cell targets for protection of Indigenous Australians against severe influenza disease
-
Luca Hensen
The protective role of tumour-resident CD8+ T cells in virally-induced human cancers
-
Rehana V Hewavisenti
Phosphorylation dynamics and roles in the central nervous system response to interferon-α
-
Markus J Hofer
Liver tissue resident memory T cells are formed under various conditions
-
Lauren E Holz
A selective Jak1 Inhibitor, Filgotinib (GLPG0634) suppresses lymphocytic infiltration in the salivary gland of non-obese diabetic mice via suppression of BAFF, IP10 and CXCL13 production of salivary gland epithelial cells
-
seungmin Hong
Continentalic acid is responsible for anti-inflammatory and anti-arthritic activities of
Aralia continentalis
Kitag. ethanol extract in IL-1β-stimulated human osteoarthritis chondrocytes
-
Riwon Hong
Membrane-modified liposomes for vaccine delivery
-
Sarah Hook
Analysis of T cell heterogeneity at the clonal level
-
Miles Horton
Low density lipoprotein receptor-related protein 1 in inflammatory macrophages
-
Yu Hung
Depletion of macrophages in elderly, but not young, mice improves IL-2/anti-CD40 immunotherapy and increases anti-tumour cytotoxic T cell activity
-
Connie Jackaman
Signatures of acute EBV infection in peripheral B and T cell compartments
-
Katherine JL Jackson
Jak inhibitor (tofacitinib) suppresses lymphocytic infiltration in the salivary gland of NOD/Ltj mice the animal model of Sjogren’s syndrome
-
SeGwang Jang
Endothelial microvesicles and soluble markers of endothelial injury in critically ill newborns
-
Jan Janota
Ghrelin-reactive autoantibodies are increased in children with Prader-Willi Syndrome compared to BMI and age-matched controls
-
Penny Jeffery
Optimisation of monocyte monolayer assay (mma) for determining the clinical significance of red cell antibodies
-
Ji Yu
Regulation of HLA-DR and CD38 expression in mild and severe influenza virus infection
-
Xiaoxiao Jia
The underlying mechanisms during acute viral bronchiolitis in infants and pre-school children
-
Anya C Jones
Establishing a DNA barcoding approach to track how the immune system and immunotherapies regulate metastatic breast cancer growth at the clonal level
-
Simon Junankar
Parsing the roles of innate and adaptive immune compartments in the lethal, type I IFN-driven, immunopathological disease in LCMV-infected STAT1 KO mice
-
So Ri Jung
Regional variation in specificity and avidity of serum-specific IgE recognition of major group 1 allergens from temperate and subtropical grass pollen in Australia
-
Thina H. Kailaivasan
Investigation into the modulation of the red blood cell cytokine profile with non-small cell lung carcinoma and the resulting effect on T-cell activity
-
Elisabeth Karsten
Human hypoxic proximal tubule epithelial cells modulate CD1c
+
dendritic cell function
-
Andrew Kassianos
Deletion of the epigenetic modifier proteins Suv39h1 and Suv39h2 causes premature immune aging
-
Christine R Keenan
Characterizing MAIT cells in human mucosal cancers
-
Jason Kelly
Functional genomics approaches to identifying the role of T-bet mediated inflammation in ankylosing spondylitis
-
Tony J Kenna
Vaccine and 4–1BB co-stimulation confers protection against acute myeloid leukemia in mice
-
Daniel Kerage
A dendritic cell targeted adenoviral vector facilitates adaptive immune response against human glioma antigen (CMV-IE) and prolongs survival in a human glioma tumor model
-
Julius W Kim
Association between psoriasis and malignancy in the adult general population of United States
-
Sunmi Kim
Innate lymphoid cell response to BCG vaccination in mice
-
Joanna R Kirman
Lipid excess suppresses NK cell function in B cell lymphoma
-
Takumi Kobayashi
Suppression of murine tumor growing through CD8+ CTLs via activated DEC-205+ dendritic cells by sequential administration of α-galactosylceramide in vivo
-
Hideki Kogo
Deciphering the epigenetic regulation of humoral responses
-
Isabella Y Kong
The impact of
Staphylococcal
secretomes on cytokine induction and mitochondrial metabolism in skin epithelial cells
-
Annika Krueger
EphA4-Fc antibody treatment exerts protective action in C57BL/6 mice subjected to acute enterobacterial peritonitis
-
Vijay Dr Kumar
Changes in peripheral T-cell subsets during Tuberculosis-Diabetes Co-morbidity
-
Carine Kunsevi-Kilola
HPV16E7 induced hyperplasia promotes CXCL9/10 expression and induces CXCR3
+
T cell migration to skin
-
Paula Kuo
The regulation of SMG1 in innate immunity via alternative splicing coupled to nonsense-mediated mRNA decay
-
HUI-CHI LAI
Eliciting innate and adaptive anti-tumour immunity by nanoemulsion co-delivery of tumour antigen and nkt cell ligand to cd8α
+
dcs
-
Pui Yeng Lam
MIF regulates NLRP3 inflammasome activation and release of IL-1 family cytokines
-
Tali Lang
An IgG-binding mutant of staphylococcal superantigen-like protein 10 (ssl10) reveals an additional role in complement evasion
-
Ries J Langley
PI3K-δ specific inhibition of regulatory T cells controls metastatic breast cancer via the development of specific anti-tumour T cells
-
Sarah N Lauder
Increased recruitment of tubulointerstitial human gamma-delta t cells in renal fibrosis and chronic kidney disease
-
Becker Law
Characterisation of EBV-specific CD8+ T cells in patients with Diffuse Large B-cell Lymphoma
-
Soi Cheng Law
Type 1 interferon signalling to dendritic cells limits Murid Herpesvirus-4 spread from the olfactory epithelium
-
Clara Lawler
Immunological mechanisms of chicken susceptibility to H7N9 influenza in the absence of a MBCS
-
Daniel Layton
The development of immune cell subsets expressing Type 2 cytokines in response to parasites and allergens
-
Graham Le Gros
Vitamin D supplementation alleviates Th2 immune response by modulating regulatory T cells and memory T cells
-
Hyun Soo Lee
Clodronate liposome-induced macrophage depletion prevents UVR-induced immunosuppression
-
James S Lee
Association of a novel long non-coding RNA in 21q22 with Ankylosing Spondylitis susceptibility
-
candice lee
Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin
-
Graham R Leggatt
A toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population
-
Chih-Hsiang Leng
CD4
+
T cell responses in different age-sex groups of a semelparous marsupial species, the red-tailed phascogale
(phascogale calura)
-
Corinne Letendre
Estrogen reduces pd-l1 expression in estrogen-receptor positive (er
+
) breast cancer cells
in vitro
-
Hongzhuo Li
Step-wise engagement of the killer T cell function underscored by H3K27me3 demethylation
-
Jasmine Li
Immunological function of alternatively spliced isoforms of MR1
-
Shihan Li
Spleen stromal niches which support myeloid restricted hematopoiesis
-
Hong Kiat (Don) Lim
Unraveling the dynamics of fate in emergency haematopoiesis using cellular barcoding
-
Dawn Lin
Identification of common host cell transcriptional responses to bacterial infections for drug repurposing
-
Chun Liu
Dissecting the immunological mechanisms underlying the efficacy of neoadjuvant immunotherapy
-
Jing Liu
Recombinant lipidated E6E7 of HPV induce strong anti-tumor immunity in animal model
-
Shih-Jen Liu
An optimized live-cell microscopy assay reveals human T-cells primarily respond chemokinetically to chemokines, in contrast to the chemotactic responses of human dendritic cells
-
Evert J. Loef
An examination of the persistence and immunogenicity of
Plasmodium
blood-stage parasites following commencement of chemoprophylaxis with delayed death antimalarial drugs
-
Leanne Low
High affinity single TCR clone drives a terminally differentiated poly-functional cytotoxic T cell response against viral infection contributing to viral clearance
-
Fabio Luciani
Roles for complement C5a receptors, C5aR1 and C5aR2, in regulating melanoma growth
-
Helga Manthey
Different populations of CD11b
+
dendritic cells drive Th2 responses in the small intestine and colon
-
Johannes U Mayer
Identifying human regulatory B cells activated by IL-4-treated mast cells or their microvesicles by mass cytometry
-
Felix Marsh-Wakefield
Gene variants of interleukin receptors and their involvement in inherited canine inflammatory diseases: Serendipity or designation?
-
Hamutal Mazrier
The regulatory effects of mucosal associated invariant t (MAIT) cells in cancer
-
Tobias Meredith
New CARs to enhance cancer immunotherapy in pediatric tumors
-
Deborah Meyran
Gene expression profiling reveals the molecular signature of severe carbamazepine-induced hypersensitivity reactions
-
Nicole Mifsud
Distinctive cellular immunity residues at the at the human fetomaternal interface
-
John Miles
Are you my MAIT?
Understanding the role of MAIT cells in colorectal liver metastasis
-
Rosemary Millen
Expression of an
enterotoxigenic Escherichia coli
fusion protein, colonization factor B-heat labile toxin B sub unit (CfaB-LTB), in transgenic plant as edible vaccine candidate
-
Seyed Mohammad Moazzeni
IL-22 as a potential therapy to boost mucosal wound healing in the lung
-
Md Moniruzzaman
Ablation of commensal microbiota-derived signalling impairs the development of antibody responses to influenza vaccination
-
Anna H Mooney
Where and how memory cells are reactivated in the secondary antibody response in the lymph node
-
Imogen Moran
Therapeutic effect of Schwann cell-derived exosome on animal model of multiple sclerosis
-
Ghasem Mosayebi
The impact of TLR7 and TLR8 gene variations on antiviral immunity and asthma
-
Liisa Murray
Organoid models to investigate novel treatment options for peritoneal metastases from colorectal cancer
-
Vignesh Narasimhan
Tlr4 promote interferon type 1 expression and enhance the th2 response to nippostrongylus brasiliensis independantly of neutrophils extracellular traps secretion
-
Christophe Pellefigues
Investigating squamous cell cancer immune evasion in a human cancer progression model
-
Katharina Noske
Age-related decline in primary CD8 T cell responses is associated with the development of senescence in virtual memory CD8 T cells
-
Kylie M Quinn
IL-15 dependent melanoma-resident CD8+ T cell numbers predict patient survival and outcome of anti-PD1 therapy
-
Mainthan Palendira
Nlrp3 a double edged sword in colitis and colorectal cancer
-
Agampodi Promoda Perera
Impact of dietary nanoparticles on immunity
-
Gabriela Pinget
Stability and plasticity of pathogenic ccr2-expressing t
h
17 cells
-
Maleika Osman
Skin-resident memory T cells form in the melanoma microenvironment and mediate tumour immune surveillance
-
Simone L Park
Identification of gene signatures associated with liver fibrosis by RNA-sequencing analysis of biopsies from chronic liver disease patients
-
Divya Ramnath
New Investigator Award Session
5:30PM - 7:00PM
Wednesday, 29th November
Plaza Auditorium
Chairs: Alan Baxter & Diana Hansen
Stem cell transplantation establishes T cell-dependent myeloma immune-equilibrium
-
Simone A Minnie
Sidt2 transports extracellular dsRNA into the cytoplasm for innate immune recognition
-
Tan A Nguyen
Atypical chemokine receptor 4 restrains anti-tumour CD8
+
T cell responses in breast cancer
-
Carly E Gregor
PGD2-mediated DP1 and DP2 receptor activation regulate the severity of viral bronchiolitis by controlling the production of IFN-lambda
-
Rhiannon B Werder
Development of MAIT cells
-
Hui-Fern Koay
The first identification of immunodominant CD8
+
T cell cross-reactivity across influenza types A, B and C
-
Marios Koutsakos
Educational SIG workshop
4:00PM - 5:30PM
Wednesday, 29th November
P9
The Australasian Society for Immunology Post Conference (Student Function): The Fox Hotel
7:30PM - 11:00PM
Wednesday, 29th November
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